MYP_155381
Compound 6
not Standard
13 amino acids
-
contains X representing unresolved or non-standard residue
DYAIIXYNKYXNC
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0136542
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
is attached to thioether-acyl moiety (-S-Ac-) forms a macrocycle through the side chain of the underlined cysteine residue
Amidation
MeYMe= N-methyl-4-O-methyl-tyrosine, Z = MeF= N-methyl-phenylalanine, B = MeS= N-methyl-serine, J = MeG= N-methyl-glycine, U = MeL= N-methyl-leucine, D-Y, D-tyrosine. C-terminal = NH2 at 6; selenocysteine at 11; MeYMe= N-methyl-4-O-methyl-tyrosine, Z = MeF= N-methyl-phenylalanine, B = MeS= N-methyl-serine, J = MeG= N-methyl-glycine, U = MeL= N-methyl-leucine, D-Y, D-tyrosine. C-terminal = NH2; Thioether linkage
Bio-Activity Profile
Dengue virus serotype 2 NS2B-NS3 protease
20 μM
IC50
RECORD: Rec_0200032
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
is attached to thioether-acyl moiety (-S-Ac-) forms a macrocycle through the side chain of the underlined cysteine residue
Amidation
MeYMe= N-methyl-4-O-methyl-tyrosine, Z = MeF= N-methyl-phenylalanine, B = MeS= N-methyl-serine, J = MeG= N-methyl-glycine, U = MeL= N-methyl-leucine, D-Y, D-tyrosine. C-terminal = NH2 at 6; selenocysteine at 11; MeYMe= N-methyl-4-O-methyl-tyrosine, Z = MeF= N-methyl-phenylalanine, B = MeS= N-methyl-serine, J = MeG= N-methyl-glycine, U = MeL= N-methyl-leucine, D-Y, D-tyrosine. C-terminal = NH2; Thioether linkage
Bio-Activity Profile
Zika virus NS2B-NS3 protease
3.2±0.4 μM
IC50
RECORD: Rec_0203364
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
is attached to thioether-acyl moiety (-S-Ac-) forms a macrocycle through the side chain of the underlined cysteine residue
Amidation
MeYMe= N-methyl-4-O-methyl-tyrosine, Z = MeF= N-methyl-phenylalanine, B = MeS= N-methyl-serine, J = MeG= N-methyl-glycine, U = MeL= N-methyl-leucine, D-Y, D-tyrosine. C-terminal = NH2 at 6; selenocysteine at 11; MeYMe= N-methyl-4-O-methyl-tyrosine, Z = MeF= N-methyl-phenylalanine, B = MeS= N-methyl-serine, J = MeG= N-methyl-glycine, U = MeL= N-methyl-leucine, D-Y, D-tyrosine. C-terminal = NH2; Thioether linkage
Bio-Activity Profile
West Nile virus NS2B-NS3 protease
20 μM
IC50