Peptide Database

Peptide NameBovine Beta-defensin 8

Function Ontology

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Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC176H287N59O47S8

DescriptionStandard

        VRNPQSCRWNMGVCIPISCPGNMRQIGTCFGPRVPCCR
    

Molecular Weight4238.05 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)4.67

Net Charge (pH 7.4) 4.38

Charge Density (pH 7.0) 0.1230

GRAVY Index-0.13

Hydrophobic Moment 0.43

Boman Index-0.06

Instability Index68.36

Aliphatic Index 53.68

Aromaticity 0.0526

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1697.50

LogP -20.61

H-bond Donors 64.0

H-bond Acceptors 60.0

Rotatable Bonds 130.0

Heavy Atoms 290.0

Ring Count 8.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0382179 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)