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MYP_155262
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Basic Information
Syn-BNP (1)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
13 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
FXISFSSXFSVIX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0095076 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Orn, Small letters indicate D-amino acids, N-cap: HMA, anticancer peptide at 2,8,13; Orn, Small letters indicate D-amino acids, N-cap: HMA, anticancer peptide
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
A. baumanni
32 μg/mL
MIC
PMID28055186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28055186/
RECORD: Rec_0104801 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Orn, Small letters indicate D-amino acids, N-cap: HMA, anticancer peptide at 2,8,13; Orn, Small letters indicate D-amino acids, N-cap: HMA, anticancer peptide
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa
128 μg/mL
MIC
PMID28055186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28055186/
RECORD: Rec_0136727 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Orn, Small letters indicate D-amino acids, N-cap: HMA, anticancer peptide at 2,8,13; Orn, Small letters indicate D-amino acids, N-cap: HMA, anticancer peptide
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae
64 μg/mL
MIC
PMID28055186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28055186/
RECORD: Rec_0157706 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Orn, Small letters indicate D-amino acids, N-cap: Decanoyl, anticancer peptide at 2,8,13; Orn, Small letters indicate D-amino acids, N-cap: Decanoyl, anticancer peptide
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
128 μg/mL
MIC
PMID28055186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28055186/
RECORD: Rec_0212907 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
C14OH
None
f=D-Phe; x=D-Orn; i=D-Ile; s=D-Ser; X=Orn
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 28055186 PMID28055186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28055186/
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