Peptide Database

Peptide NameHMG-CoA reductase inhibitor

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ HMG-CoA-reductase-inhibitor

Enzyme modulation ▸ Enzyme inhibition ▸ HMG-CoA Reductase Inhibitory

Metabolic ▸ Lipid metabolism ▸ Lipid-lowering activity

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC18H34N4O5

DescriptionStandard

        VGVL
    

Molecular Weight386.49 Da

Isoelectric Point (pI)5.50

Net Charge (pH 7.0)-0.27

Net Charge (pH 7.4) -0.48

Charge Density (pH 7.0) -0.0665

GRAVY Index2.95

Hydrophobic Moment 0.24

Boman Index0.93

Instability Index-13.72

Aliphatic Index 242.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 150.62

LogP -0.16

H-bond Donors 5.0

H-bond Acceptors 5.0

Rotatable Bonds 11.0

Heavy Atoms 27.0

Ring Count 0.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0219275 VERIFIED: YES

Provenance & Taxonomy

OrganismAmaranthus hypochondriacus [Plant]

Tax ID28502

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

HMG-CoA-reductase-inhibitor

RECORD: Rec_0343415 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hypolipidemic HMG-CoA Reductase Inhibitory

TargetHMG-CoA reductase