Peptide Database

Peptide NameB1-Leu

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC97H165N27O16

DescriptionStandard

        VKRFKKFFRKLKKLV
    

Molecular Weight1965.52 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.73

Net Charge (pH 7.4) 7.51

Charge Density (pH 7.0) 0.5152

GRAVY Index-0.53

Hydrophobic Moment 0.95

Boman Index-0.41

Instability Index2.15

Aliphatic Index 90.67

Aromaticity 0.2000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 750.64

LogP -1.38

H-bond Donors 28.0

H-bond Acceptors 24.0

Rotatable Bonds 73.0

Heavy Atoms 140.0

Ring Count 3.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0286320 VERIFIED: YES

Provenance & Taxonomy

OrganismCathelicidin-BF15 C-terminal amidated derivative B1 [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetK562

Activity1.1 μM

MethodIC50

RECORD: Rec_0376223 VERIFIED: YES