Peptide Database

Peptide NameSARS-CoV-2-S (1175-1205), IPB04

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV

Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC152H261N43O52

DescriptionStandard

        SVVNIQKEIDRLNEVAKNLNESLIDLQELGK
    

Molecular Weight3522.96 Da

Isoelectric Point (pI)4.66

Net Charge (pH 7.0)-2.53

Net Charge (pH 7.4) -2.75

Charge Density (pH 7.0) -0.0816

GRAVY Index-0.43

Hydrophobic Moment 0.70

Boman Index-0.10

Instability Index47.84

Aliphatic Index 131.94

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1599.08

LogP -15.99

H-bond Donors 52.0

H-bond Acceptors 50.0

Rotatable Bonds 128.0

Heavy Atoms 247.0

Ring Count 0.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417564 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermChol

Bio-Activity Profile

Function

Antimicrobial Anti-SARS-CoV-2

TargetVesicular Stomatitis Virus (VSV):inhibition of Pseudovirus (PsV) infection in 293T/ACE2 cells

Activity50 μM

MethodIC50

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