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MYP_155168
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Basic Information
CLP-4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XLWKNR
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0049596 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Dap, has a lipid tail consisting of 12-guanidinododecanoic acid at 1; Dap, has a lipid tail consisting of 12-guanidinododecanoic acid
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus mutans JF243
3 μg/mL
MIC
PMID28533236 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28533236/
RECORD: Rec_0060393 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Dap, has a lipid tail consisting of 12-guanidinododecanoic acid at 1; Dap, has a lipid tail consisting of 12-guanidinododecanoic acid
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus mutans ATCC 25175
3 μg/mL
MIC
PMID28533236 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28533236/
RECORD: Rec_0080520 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Dap, has a lipid tail consisting of 12-guanidinododecanoic acid at 1; Dap, has a lipid tail consisting of 12-guanidinododecanoic acid
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus mutans 768
2 μg/mL
MIC
PMID28533236 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28533236/
RECORD: Rec_0101419 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Dap, has a lipid tail consisting of 12-guanidinododecanoic acid at 1; Dap, has a lipid tail consisting of 12-guanidinododecanoic acid
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus mutans 568-2v-5
2 μg/mL
MIC
PMID28533236 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28533236/
RECORD: Rec_0115655 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Dap, has a lipid tail consisting of 12-guanidinododecanoic acid at 1; Dap, has a lipid tail consisting of 12-guanidinododecanoic acid
Bio-Activity Profile
Hemolytic
human RBCs
1000 μg/mL
Hemolysis
PMID28533236 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28533236/
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