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MYP_155131
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Basic Information
Heterin-2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
24 amino acids
C123H197N29O31
Standard
Sequence
FWGALAKGALKLIPSLVSSFTKKD
Physicochemical Analysis
2578.06 Da
10.00
2.76
2.55
0.1150
0.39
0.56
0.22
2.42
105.83
0.1250
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
961.92
-6.18
34.0
34.0
85.0
183.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0248636 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Heterometrus spinifer [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus megaterium AB 90008; Micrococcus luteus AB2010179
415.8-30 μM
MIC
PaperGenomic and functional characterization of three new venom peptides from the scorpion Heterometrus spinifer
RECORD: Rec_0268358 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Heterometrus spinifer [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus AB 94004
5.6 μM
MIC
PaperGenomic and functional characterization of three new venom peptides from the scorpion Heterometrus spinifer
RECORD: Rec_0341298 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0364245 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Heterometrus spinifer [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli DH5alpha, P. fluorences PF, P. putida PP
15.8-40 μM
MIC
PaperGenomic and functional characterization of three new venom peptides from the scorpion Heterometrus spinifer
RECORD: Rec_0391469 VERIFIED: YES
Provenance & Taxonomy
Heterometrus spinifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
15.8 μM
MIC
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