Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length177 amino acids

Chemical FormulaC862H1373N257O249S10

DescriptionStandard

        MSRKFRYGLSAVVLALIAAGASAPEILDQFLDEKEGNHTTAYRDGAGIWTICRGATRVDGKPVIPGMKLSKEKCDRVNAIERDKALAWVEKNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRINAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQVSRRDQESALACWGIDR
    

Molecular Weight19641.35 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)9.53

Net Charge (pH 7.4) 9.09

Charge Density (pH 7.0) 0.0538

GRAVY Index-0.44

Hydrophobic Moment 0.73

Boman Index-0.09

Instability Index42.04

Aliphatic Index 74.52

Aromaticity 0.0847

Extinction Coeff. Reduced 34950.00

Extinction Coeff. Oxidized 35450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8201.50

LogP -88.08

H-bond Donors 297.0

H-bond Acceptors 270.0

Rotatable Bonds 655.0

Heavy Atoms 1378.0

Ring Count 29.0

Amide Bonds 187.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084041 VERIFIED: NO

Provenance & Taxonomy

OrganismShigella dysenteriae [Bacterium]

FamilyLysozyme

Tax ID622

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0121153 VERIFIED: YES

Provenance & Taxonomy

OrganismShigella phage POCJ13 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic