Peptide Database

Peptide Namegrowth hormone 2

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length191 amino acids

Chemical FormulaC1002H1560N268O296S7

DescriptionStandard

        FPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEAYILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLRSVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
    

Molecular Weight22321.18 Da

Isoelectric Point (pI)7.81

Net Charge (pH 7.0)0.92

Net Charge (pH 7.4) 0.50

Charge Density (pH 7.0) 0.0048

GRAVY Index-0.40

Hydrophobic Moment 0.73

Boman Index-0.06

Instability Index45.18

Aliphatic Index 87.28

Aromaticity 0.1204

Extinction Coeff. Reduced 25900.00

Extinction Coeff. Oxidized 26150.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 9221.95

LogP -109.94

H-bond Donors 324.0

H-bond Acceptors 306.0

Rotatable Bonds 701.0

Heavy Atoms 1573.0

Ring Count 34.0

Amide Bonds 212.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0243600 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted disulphide bond formation between cysteine residues at positions 53 and 165, and 182 and 189; predicted N-linked glycosylation on asparagine residue at position 140

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetGrowth hormone receptor (Human)