Peptide Database

Peptide NameCycloviolacin H4

Function Ontology

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Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC129H209N35O37S6

DescriptionStandard

        GIPCGESCVWIPCISAAIGCSCKSKVCYR
    

Molecular Weight3034.64 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0586

GRAVY Index0.67

Hydrophobic Moment 0.28

Boman Index0.22

Instability Index14.71

Aliphatic Index 80.69

Aromaticity 0.0690

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1128.72

LogP -11.98

H-bond Donors 46.0

H-bond Acceptors 45.0

Rotatable Bonds 94.0

Heavy Atoms 207.0

Ring Count 5.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0094231 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)