Peptide Database

Peptide Namecycloviolacin O2

Function Ontology

Antiparasitic ▸ Anthelminthic

Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC130H210N36O39S5

DescriptionStandard

        GIPGESCVWIPCISSAIGCSCKSKVCYRN
    

Molecular Weight3061.60 Da

Isoelectric Point (pI)8.42

Net Charge (pH 7.0)1.71

Net Charge (pH 7.4) 1.43

Charge Density (pH 7.0) 0.0590

GRAVY Index0.37

Hydrophobic Moment 0.35

Boman Index0.16

Instability Index28.20

Aliphatic Index 77.24

Aromaticity 0.0690

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1192.04

LogP -14.06

H-bond Donors 47.0

H-bond Acceptors 46.0

Rotatable Bonds 96.0

Heavy Atoms 210.0

Ring Count 5.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237952 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Nematocidal Anthelmintic

TargetHaemonchus contortus

Activity0.12

MethodIC50

RECORD: Rec_0366194 VERIFIED: YES