Peptide Database

Peptide NameNeuropeptide-like peptide nlp-30-5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antifungal

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC40H46N8O10

DescriptionStandard

        PYGGYGW
    

Molecular Weight798.84 Da

Isoelectric Point (pI)5.95

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.10

Charge Density (pH 7.0) -0.0062

GRAVY Index-0.90

Hydrophobic Moment 0.13

Boman Index0.41

Instability Index7.44

Aliphatic Index 0.00

Aromaticity 0.4286

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 280.18

LogP -0.75

H-bond Donors 11.0

H-bond Acceptors 10.0

Rotatable Bonds 19.0

Heavy Atoms 58.0

Ring Count 5.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038293 VERIFIED: NO

Provenance & Taxonomy

OrganismCaenorhabditis elegans [Animal]

Tax ID6239

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0084757 VERIFIED: YES

Provenance & Taxonomy

OrganismCaenorhabditis elegans [Animal]

FamilyPYGGYGW-amide

Tax ID6239

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Neuropeptide Neuromodulator

Half-LifeMammalian: >20 hour; Yeast: >20 hour; E. coli: ?

RECORD: Rec_0156571 VERIFIED: YES

Provenance & Taxonomy

OrganismCaenorhabditis elegans [Animal]

FamilyPYGGYGW-amide

Tax ID6239

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibacterial Antifungal Neuropeptide Neuromodulator

Half-LifeMammalian: >20 hour; Yeast: >20 hour; E. coli: ?

RECORD: Rec_0241597 VERIFIED: NO

Provenance & Taxonomy

OrganismCaenorhabditis elegans [Animal]

FamilyYGGW-amide related peptide

Tax ID6239

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Opioid Neuropeptide

RECORD: Rec_0300423 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/