Peptide Database

Peptide NameAngiotensin I converting enzyme inhibitior 2

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC36H62N12O13

DescriptionStandard

        PKDLREN
    

Molecular Weight870.95 Da

Isoelectric Point (pI)6.49

Net Charge (pH 7.0)-0.04

Net Charge (pH 7.4) -0.10

Charge Density (pH 7.0) -0.0055

GRAVY Index-2.39

Hydrophobic Moment 0.51

Boman Index-0.75

Instability Index36.09

Aliphatic Index 55.71

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 429.54

LogP -4.61

H-bond Donors 15.0

H-bond Acceptors 13.0

Rotatable Bonds 30.0

Heavy Atoms 61.0

Ring Count 1.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418131 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus caballus [Animal]

Tax ID9796

Structure & Mods

Configproteolytic peptide fragment [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive

Activity9.82±0.37 μM

MethodIC50

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