Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length125 amino acids

Chemical FormulaC535H896N154O174S10

DescriptionStandard

        MKSLLLTLALFMLQAQLISGNWYVRKCGNKIGKCRSSCRKGEVPIDPPTGMCSKEKTCCVLSGQELHPAICGGTAKPTRAPVTGVTQGSEAAEASVASGASGASEAATSVAATSVATTLVATTSG
    

Molecular Weight12590.42 Da

Isoelectric Point (pI)8.95

Net Charge (pH 7.0)4.53

Net Charge (pH 7.4) 4.13

Charge Density (pH 7.0) 0.0362

GRAVY Index0.12

Hydrophobic Moment 0.71

Boman Index0.11

Instability Index23.78

Aliphatic Index 78.16

Aromaticity 0.0240

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5205.29

LogP -70.30

H-bond Donors 190.0

H-bond Acceptors 190.0

Rotatable Bonds 415.0

Heavy Atoms 873.0

Ring Count 11.0

Amide Bonds 130.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0205811 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence