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MYP_154740
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Basic Information
Lantibiotic lichenicidin VK21 A2 (LchA2; Lchbeta; Bacteriocin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
32 amino acids
C133H223N37O48S4
Standard
Sequence
TTPATTSSWTCITAGVTVSASLCPTTKCTSRC
Physicochemical Analysis
3236.67 Da
8.52
1.36
1.11
0.0424
0.26
0.41
0.12
36.60
51.88
0.0312
5500.00
5750.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1355.00
-22.86
55.0
54.0
96.0
222.0
4.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0131565 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
SS2
16.6 μM
IC50
PaperPubMed PMID: 19561184 | PubMed PMID: 19707558 | PubMed PMID: 20578714 PMID19561184;19707558;20578714 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19561184/
RECORD: Rec_0134439 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus B1314
2.6 μM
IC50
PaperPubMed PMID: 19561184 | PubMed PMID: 19707558 | PubMed PMID: 20578714 PMID19561184;19707558;20578714 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19561184/
RECORD: Rec_0156890 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
1-Thr: 2-oxobutanoic acid; 2-Thr: (Z)-2,3-didehydrobutyrine; 5-Thr: (Z)-2,3-didehydrobutyrine; 6-Thr: (Z)-2,3-didehydrobutyrine; 8-Ser: 2,3-didehydroalanine (Ser); 13-Thr: (Z)-2,3-didehydrobutyrine; 17-Thr: (Z)-2,3-didehydrobutyrine; 26-Thr: (Z)-2,3-didehydrobutyrine
Bio-Activity Profile
Antimicrobial Host defense
PaperPDB 2KTO structural record; NMR; chain A; residues 2-32
RECORD: Rec_0167774 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Only Lchbeta: Bacillus megaterium VKM41
2 μM
IC50
PaperPubMed PMID: 19561184 | PubMed PMID: 19707558 | PubMed PMID: 20578714 PMID19561184;19707558;20578714 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19561184/
RECORD: Rec_0174346 VERIFIED: YES
Provenance & Taxonomy
Bacillus licheniformis [Bacterium]
Bacteriocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID20578714 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20578714/
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