Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length476 amino acids

Chemical FormulaC2368H3762N578O681S31

DescriptionStandard

        MMLLLLLLLAPQASVAQPGVKLMMSSKGLDYVTNVITGWAQEKLLTTDIPQISGKVNIGIGSVYYVVYDMKVVKVDYPQPSVKFEENAGLHMELCGLSIAVTAEWRTKYGLIKDGGTLDLALFDVCVESLLQLGKDDQARLSVSTLTCKAQVGRVYTKFHGGAGILIQAFMDLFPGHIKAMTENAICPLLEKEIVNLEGVLAAMNVTYHVDPSLILNNSLTSDPVIQTSDMEVDFKGVFYSEWNPMEPPFPSKDFMLPCETGHMFTLGISQFCLNSYAYACLTAGLLQINVTDSMIPQKSPVRLNTSYFGPFIPQLPKMFPNMLMKLQVFADEAPAVSLQMDSLSLLLSAAVKAYAIDNTTTLHPLFTLNLTTQFSGKLNIANEKLMGKMGFDNLTLSLASSEIGTFQTTTLKNVAIMGMKNGFLPKLNEMLQRGFPLPLMKGVALVKTVLQVQKGFLAVFSDVQISPPLYTEEEL
    

Molecular Weight52218.68 Da

Isoelectric Point (pI)5.37

Net Charge (pH 7.0)-8.01

Net Charge (pH 7.4) -8.74

Charge Density (pH 7.0) -0.0168

GRAVY Index0.25

Hydrophobic Moment 0.65

Boman Index0.20

Instability Index34.48

Aliphatic Index 102.79

Aromaticity 0.0840

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37735.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0206300 VERIFIED: NO

Provenance & Taxonomy

OrganismClupea harengus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria