Peptide Database

Peptide NameAlpha-defensin 14 (Defensin-related cryptdin-14)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC397H646N124O136S8

DescriptionStandard

        ALVLLAFQVQADPIQNTDEETKTEEQPGEDDQAVSVSFGDPEGSSLQEESLRDLVCYCRTRGCKRRERMNGTCRKGHLMHTLCCR
    

Molecular Weight9588.65 Da

Isoelectric Point (pI)5.08

Net Charge (pH 7.0)-4.06

Net Charge (pH 7.4) -4.46

Charge Density (pH 7.0) -0.0478

GRAVY Index-0.75

Hydrophobic Moment 0.59

Boman Index-0.22

Instability Index53.28

Aliphatic Index 63.06

Aromaticity 0.0353

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4258.95

LogP -52.63

H-bond Donors 153.0

H-bond Acceptors 142.0

Rotatable Bonds 327.0

Heavy Atoms 665.0

Ring Count 8.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0402153 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

TargetNo Target Organism Found