Peptide Database

Peptide NameIFN-κ

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length180 amino acids

Chemical FormulaC996H1538N276O279S11

DescriptionStandard

        LDCNLLNVHLRRVTWQNLRHLSSMSNSFPVECLRENIAFELPQEFLQYTQPMKRDIKKAFYEMSLQAFNIFSQHTFKYWKERHLKQIQIGLDQQAEYLNQCLEEDKNENEDMKEMKENEMKPSEARVPQLSSLELRRYFHRIDNFLKEKKYSDCAWEIVRVEIRRCLYYFYKFTALFRRK
    

Molecular Weight22195.26 Da

Isoelectric Point (pI)8.75

Net Charge (pH 7.0)4.18

Net Charge (pH 7.4) 3.58

Charge Density (pH 7.0) 0.0232

GRAVY Index-0.78

Hydrophobic Moment 0.81

Boman Index-0.20

Instability Index67.17

Aliphatic Index 74.22

Aromaticity 0.1333

Extinction Coeff. Reduced 29910.00

Extinction Coeff. Oxidized 30160.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 9164.00

LogP -93.83

H-bond Donors 321.0

H-bond Acceptors 299.0

Rotatable Bonds 693.0

Heavy Atoms 1562.0

Ring Count 37.0

Amide Bonds 202.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0293052 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted disulphide bond formation between cysteine residues at positions 3 and 101, and 32 and 154

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetInterferon-α/β receptor (Human)