Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC399H616N104O105S11

DescriptionStandard

        MATCKKIFYFVFALFFILAQLPSGCKAGLEYSQSFPGGEFAVCETCRLGRGKCRKVCMEEEKVDGYCKLNFFCCRQRV
    

Molecular Weight8902.51 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)4.42

Net Charge (pH 7.4) 4.05

Charge Density (pH 7.0) 0.0567

GRAVY Index0.14

Hydrophobic Moment 0.63

Boman Index0.05

Instability Index37.76

Aliphatic Index 65.00

Aromaticity 0.1538

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3373.38

LogP -26.89

H-bond Donors 127.0

H-bond Acceptors 121.0

Rotatable Bonds 297.0

Heavy Atoms 619.0

Ring Count 14.0

Amide Bonds 81.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0061411 VERIFIED: NO

Provenance & Taxonomy

OrganismCastor canadensis [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin