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MYP_154668
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Basic Information
Unnamed
Annotation / Sequence feature ▸ Secretory pathway ▸ Secreted protein
Cardiovascular
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Reproductive biology ▸ Reproductive modulation
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic
Standard
10 amino acids
C62H89N17O14
Standard
Sequence
DRVYIHPFHL
Physicochemical Analysis
1296.48 Da
6.92
-0.07
-0.37
-0.0065
-0.20
0.34
0.09
22.64
107.00
0.2000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
493.22
-1.12
17.0
16.0
37.0
93.0
5.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001055 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0029622 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Angiotensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
Hormonal Cardiovascular
Primary endothelial cells + fetal calf serum 10% + ACE inhibitor MK422 + heat inactivation
Radioimmunoassay
9.9 min
PaperAn in vitro system for study of effects of angiotensin I on cultured endothelial cells
RECORD: Rec_0056153 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Angiotensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
Hormonal Cardiovascular
Primary endothelial cells + fetal calf serum 2.5%
Radioimmunoassay
9.2 min
PaperAn in vitro system for study of effects of angiotensin I on cultured endothelial cells
RECORD: Rec_0060319 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
ACE-inhibitory peptide
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperVPPIPP and IPPVPP: two hexapeptides innovated to exert antihypertensive activity. PMID23638059 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23638059/
RECORD: Rec_0066901 VERIFIED: YES
Provenance & Taxonomy
Callithrix jacchus [Animal]
Serpin
9483
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Secreted protein
PMID4344907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4344907/
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