Peptide Database

Peptide NameE3 ubiquitin-protein ligase TRIM11

Function Ontology

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Retroviral restriction factor

Standard StatusStandard

Sequence Length468 amino acids

Chemical FormulaC2307H3666N678O690S26

DescriptionStandard

        MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLVETLRRFRGDVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRKEKGELSAGNGFWILVFLGSYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPLSSSPTPMTICRPKGGSGDTLAPQ
    

Molecular Weight52773.61 Da

Isoelectric Point (pI)5.50

Net Charge (pH 7.0)-11.67

Net Charge (pH 7.4) -12.78

Charge Density (pH 7.0) -0.0249

GRAVY Index-0.45

Hydrophobic Moment 0.85

Boman Index-0.09

Instability Index65.53

Aliphatic Index 82.78

Aromaticity 0.0620

Extinction Coeff. Reduced 43430.00

Extinction Coeff. Oxidized 44555.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0362448 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTRIM

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Anti-HIV-1 Entry inhibitor Retroviral restriction factor

TargetHuman immunodeficiency virus type 1 (HIV-1)