Peptide Database

Peptide NameBeta-defensin 128

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC483H787N125O129S7

DescriptionStandard

        MKLFLVLIILLFEVLTDGARLKKCFNNVTGYCRKKCKVGEIHEIGCLSGKLCCVNDEENKKHVPFKKPHQQPVEKLSVQQDYVILPTITIFTV
    

Molecular Weight10633.63 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)4.71

Net Charge (pH 7.4) 4.22

Charge Density (pH 7.0) 0.0506

GRAVY Index0.08

Hydrophobic Moment 0.62

Boman Index0.06

Instability Index30.10

Aliphatic Index 107.74

Aromaticity 0.0753

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4089.93

LogP -28.93

H-bond Donors 143.0

H-bond Acceptors 144.0

Rotatable Bonds 363.0

Heavy Atoms 744.0

Ring Count 14.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0325532 VERIFIED: NO

Provenance & Taxonomy

OrganismCercocebus atys [Animal]

FamilyDefensin

Tax ID9531

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

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