Peptide Database

Peptide NameG4-11A gliadin (p62-p75; E65 and A72)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC78H112N16O21

DescriptionStandard

        PQPELPYPQPALPY
    

Molecular Weight1609.82 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.04

Net Charge (pH 7.4) -1.10

Charge Density (pH 7.0) -0.0743

GRAVY Index-0.95

Hydrophobic Moment 0.13

Boman Index0.11

Instability Index126.81

Aliphatic Index 62.86

Aromaticity 0.1429

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 547.62

LogP -1.94

H-bond Donors 15.0

H-bond Acceptors 20.0

Rotatable Bonds 39.0

Heavy Atoms 115.0

Ring Count 8.0

Amide Bonds 15.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0417368 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: G4; Reported substitutions/positions: E65; Reported substitutions/positions: A72; Reported substitution variant

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay