Peptide Database

Peptide NameIL-17B

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length160 amino acids

Chemical FormulaC785H1275N241O224S15

DescriptionStandard

        QPRSPKSKRKGQGRPGPLAPGPHQVPLDLVSRMKPYARMEEYERNIEEMVAQLRNSSELAQRKCEVNLQLWMSNKRSLSPWGYSINHDPSRIPVDLPEARCLCLGCVNPFTMQEDRSMVSVPVFSQVPVRRRLCPPPPRTGPCRQRAVMETIAVGCTCIF
    

Molecular Weight18153.98 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)9.88

Net Charge (pH 7.4) 9.42

Charge Density (pH 7.0) 0.0617

GRAVY Index-0.56

Hydrophobic Moment 0.62

Boman Index-0.15

Instability Index83.38

Aliphatic Index 69.38

Aromaticity 0.0500

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7446.83

LogP -79.10

H-bond Donors 262.0

H-bond Acceptors 251.0

Rotatable Bonds 585.0

Heavy Atoms 1265.0

Ring Count 32.0

Amide Bonds 174.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0139710 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted N-linked glycosylation of asparagine residue at position 55; predicted disulphide bond formation between cysteine residues at positions 101 and 156, and 106 and 158.

Bio-Activity Profile

Function

Receptor agonist Immunomodulatory Signaling peptide

TargetInterleukin-25 receptor (Human)