Peptide Database

Peptide NameDQ2-y-IV y-Glia (p117p132; E125)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC81H117N23O27

DescriptionStandard

        QQFSQPQQEFPQPQQ
    

Molecular Weight1844.93 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.0825

GRAVY Index-2.10

Hydrophobic Moment 0.42

Boman Index-0.33

Instability Index145.55

Aliphatic Index 0.00

Aromaticity 0.1333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 846.60

LogP -10.83

H-bond Donors 23.0

H-bond Acceptors 26.0

Rotatable Bonds 58.0

Heavy Atoms 131.0

Ring Count 5.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354910 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E125

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay

RECORD: Rec_0405750 VERIFIED: YES