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MYP_154421
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Basic Information
Styelin A
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
19 amino acids
C95H144N28O24
Standard
Sequence
GFGKAFHSVSNFAKKHKTA
Physicochemical Analysis
2062.33 Da
10.48
3.93
3.62
0.2069
-0.56
0.61
-0.03
9.56
31.05
0.1579
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
852.34
-9.48
30.0
30.0
69.0
147.0
5.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0287852 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa MR 3007
4 μg/mL
MIC
PMID9467865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9467865/
RECORD: Rec_0329617 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium 14028S
5 μg/mL
MIC
PMID9467865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9467865/
RECORD: Rec_0351849 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis 94132
2 μg/mL
MIC
PMID9467865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9467865/
RECORD: Rec_0373927 VERIFIED: YES
Provenance & Taxonomy
Sea squirt [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
1-2 μg/mL
MIC
PaperStyelins, broad-spectrum antimicrobial peptides from the solitary tunicate, Styela clava.
RECORD: Rec_0379158 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
7725
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antiviral Anti-HIV-1 Entry inhibition
HIV-1 IIIB | CEM-SS cells
48.8 μM
EC50
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperIdentification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Wang G, Watson KM, Peterkofsky A, Buckheit RW Jr. | Antimicrob Agents Chemother. 2010 Mar;54(3):1343-6. | DOI:10.1128/AAC.01448-09 | PMID:20086159 PMID20086159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20086159/
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