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MYP_154421
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Basic Information
Styelin A
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
19 amino acids
C95H144N28O24
Standard
Sequence
GFGKAFHSVSNFAKKHKTA
Physicochemical Analysis
2062.33 Da
10.48
3.93
3.62
0.2069
-0.56
0.61
-0.03
9.56
31.05
0.1579
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
852.34
-9.48
30.0
30.0
69.0
147.0
5.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0218418 VERIFIED: YES
Provenance & Taxonomy
Sea squirt [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Candida albicans
~36 μg/mL
MIC
PaperStyelins, broad-spectrum antimicrobial peptides from the solitary tunicate, Styela clava.
RECORD: Rec_0237993 VERIFIED: NO
Provenance & Taxonomy
Styela clava [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPatent US 10723764 B2 Evidence URLhttps://patents.google.com/patent/US10723764B2/en PatentUS 10723764 B2
RECORD: Rec_0266086 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Listeria monocytogenes EGD
2 μg/mL
MIC
PMID9467865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9467865/
RECORD: Rec_0282256 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0286064 VERIFIED: YES
Provenance & Taxonomy
Sea squirt [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
of Enterococcus faecium
1 μg/mL
MIC
PaperStyelins, broad-spectrum antimicrobial peptides from the solitary tunicate, Styela clava.
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