Peptide Database

Peptide NameGlucagon-like peptide-2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC175H269N47O58S

DescriptionStandard

        HADGSFSDEMNTVLDNLATRDFINWLLHTKITDSL
    

Molecular Weight3991.35 Da

Isoelectric Point (pI)4.44

Net Charge (pH 7.0)-4.06

Net Charge (pH 7.4) -4.37

Charge Density (pH 7.0) -0.1159

GRAVY Index-0.27

Hydrophobic Moment 0.52

Boman Index0.04

Instability Index4.19

Aliphatic Index 92.00

Aromaticity 0.0857

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1708.47

LogP -17.82

H-bond Donors 59.0

H-bond Acceptors 57.0

Rotatable Bonds 131.0

Heavy Atoms 281.0

Ring Count 6.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0229068 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0239296 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyGlucagon

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0267778 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyGlucagon-like peptide

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Mods5:Phosphoserine; 7:Phosphoserine

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0363206 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/