Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length237 amino acids

Chemical FormulaC1200H1819N271O365S8

DescriptionStandard

        QIDDLAEVVYSLSGLPAVFQTFIDLDLKGVVFPAGNHTDSPYMAASFTIPDQSDSMLYLAFSEYFFQSSSFAYYTAGAFNMTIAEEVKSGNSFVFSLLFFPSDLSYFNINTEIFSSTMPEVAKYSITPYLVMFKLMSSEIPTISLQQDSFTAEIQGSVEVLAILPDSTTQSLFTLTIVPNTSISLNIFDQKLMGSLCLNRIQFSLAHSSAGSFEVLFLENILSYILQTEVIPSANGK
    

Molecular Weight26138.39 Da

Isoelectric Point (pI)4.07

Net Charge (pH 7.0)-16.05

Net Charge (pH 7.4) -16.42

Charge Density (pH 7.0) -0.0677

GRAVY Index0.35

Hydrophobic Moment 0.55

Boman Index0.26

Instability Index52.19

Aliphatic Index 96.29

Aromaticity 0.1350

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 14900.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0228468 VERIFIED: NO

Provenance & Taxonomy

OrganismQuiscalus mexicanus (Great-tailed grackle) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria