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MYP_154325
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Basic Information
Unnamed
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Collagen boosting
Standard
10 amino acids
C60H89N15O13
Standard
Sequence
YGGFLRKYPK
Physicochemical Analysis
1228.44 Da
10.00
2.76
2.55
0.2756
-1.07
0.56
-0.17
44.45
39.00
0.3000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
470.83
-1.76
17.0
16.0
38.0
88.0
4.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0096128 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Alpha-neoendorphin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Neuropeptide Neuromodulator Receptor modulation
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Alpha-neoendorphin (Bos taurus): PMID 6316163 PMID6316163 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6316163/
RECORD: Rec_0120872 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Alpha-neoendorphin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Receptor modulation
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
RECORD: Rec_0128374 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Enkephalin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
opioid receptor
PaperMinamino N., Kangawa K., Chino N., Sakapibara S., Matsuo H.. Beta-Neo-endorphin, a new hypothalamic "big" Leu-enkephalin of porcine origin: its purification and the complete amino acid sequence. Biochem. Biophys. Res. Commun., 99, 864-870, 1984.
RECORD: Rec_0143633 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
Opioid
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Analgesic Neuromodulator
RECORD: Rec_0167887 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Alpha-neoendorphin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Analgesic Pronociceptive Neuropeptide Neuromodulator Receptor modulation
Mammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Alpha-neoendorphin (Homo sapiens): PMID 6316163 PMID6316163 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6316163/
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