Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC695H1109N197O205S8

DescriptionStandard

        MKLSQRGIDLIKQFEGYSSKAYPDPATGGAPWTIGYGTIKGVKPGMIITAEQAEKMLRDDVAKFESGVSSLITAPTTQGQFDAMVSLAYNIGLGNFGKSTLLKKHNARCYTCAADQFRVWNRANGKVMNGLTKRRAAERQVYMS
    

Molecular Weight15760.96 Da

Isoelectric Point (pI)9.73

Net Charge (pH 7.0)8.57

Net Charge (pH 7.4) 8.24

Charge Density (pH 7.0) 0.0595

GRAVY Index-0.35

Hydrophobic Moment 0.69

Boman Index-0.01

Instability Index27.71

Aliphatic Index 70.56

Aromaticity 0.0903

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20065.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6524.59

LogP -70.23

H-bond Donors 230.0

H-bond Acceptors 223.0

Rotatable Bonds 530.0

Heavy Atoms 1105.0

Ring Count 21.0

Amide Bonds 156.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0230787 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage YX3973 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic