Peptide Database

Peptide NameARF(1-37) scr

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC197H326N64O42S2

DescriptionStandard

        FRVPLRIRPCVVAPRLVMVRHTFGRIARWVAGPLETR
    

Molecular Weight4327.23 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.84

Net Charge (pH 7.4) 6.57

Charge Density (pH 7.0) 0.1849

GRAVY Index0.24

Hydrophobic Moment 0.71

Boman Index-0.04

Instability Index44.13

Aliphatic Index 107.84

Aromaticity 0.0811

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1693.19

LogP -11.04

H-bond Donors 64.0

H-bond Acceptors 52.0

Rotatable Bonds 134.0

Heavy Atoms 305.0

Ring Count 9.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0338131 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familyp14ARF-derived

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorescein/FITC labeling

C-TermAmidation

Other ModsN-term detail: Labelled with fluorescein

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetMCF-7; MDA MB 231

MethodFluorescence-based uptake assay

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