Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length142 amino acids

Chemical FormulaC741H1133N183O225S12

DescriptionStandard

        MNLLMLTFMLCGLLTLVTKAGWFVERCWKNDIGYCRKRCLLLERYKLLCMNKQSCCIPLRSYDPYTQWPINPTFFKDLNVDYITRDDFPFSPESGFTDEVTVKATTTQESRVTEISTPTPESTEDTTFSDEPETADLYKCWD
    

Molecular Weight16589.79 Da

Isoelectric Point (pI)4.70

Net Charge (pH 7.0)-6.55

Net Charge (pH 7.4) -6.93

Charge Density (pH 7.0) -0.0461

GRAVY Index-0.36

Hydrophobic Moment 0.58

Boman Index-0.02

Instability Index50.48

Aliphatic Index 69.30

Aromaticity 0.1268

Extinction Coeff. Reduced 30940.00

Extinction Coeff. Oxidized 31440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6567.31

LogP -58.56

H-bond Donors 236.0

H-bond Acceptors 231.0

Rotatable Bonds 533.0

Heavy Atoms 1161.0

Ring Count 31.0

Amide Bonds 149.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0116951 VERIFIED: NO

Provenance & Taxonomy

OrganismMoschus moschiferus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence