Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC344H546N94O86S9

DescriptionStandard

        MKFHLFFFILLFGATILTAKKSYPEYGSLDLRKECKMRRGHCKLQCSEKELRISFCIRPGTHCCM
    

Molecular Weight7663.18 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)6.71

Net Charge (pH 7.4) 6.23

Charge Density (pH 7.0) 0.1032

GRAVY Index-0.06

Hydrophobic Moment 0.44

Boman Index-0.02

Instability Index53.96

Aliphatic Index 75.08

Aromaticity 0.1231

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2897.48

LogP -20.82

H-bond Donors 110.0

H-bond Acceptors 105.0

Rotatable Bonds 260.0

Heavy Atoms 533.0

Ring Count 13.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0054258 VERIFIED: NO

Provenance & Taxonomy

OrganismMus spicilegus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence

RECORD: Rec_0110892 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic