Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC397H620N110O105S10

DescriptionStandard

        MALIRKTFYFVFAVFFILVQQPPGCQAGLEFSEPFPSGRFAVCESCKLGRGKCRKECLENEKPDGSCRLNFLCCRQRM
    

Molecular Weight8934.49 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)4.43

Net Charge (pH 7.4) 4.08

Charge Density (pH 7.0) 0.0568

GRAVY Index-0.04

Hydrophobic Moment 0.46

Boman Index-0.02

Instability Index52.75

Aliphatic Index 65.00

Aromaticity 0.1282

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3464.49

LogP -30.44

H-bond Donors 127.0

H-bond Acceptors 120.0

Rotatable Bonds 295.0

Heavy Atoms 622.0

Ring Count 15.0

Amide Bonds 83.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0242911 VERIFIED: NO

Provenance & Taxonomy

OrganismCercocebus atys [Animal]

FamilyDefensin

Tax ID9531

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence