Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC439H727N141O141S7

DescriptionStandard

        MRTLAILAAILLFALLAQAESLQERADEAVTQEQPGEDNQDFAISLEENGLSTLRASGSQARRTCYCRIGRCFRRESSSGRCSISGRIYRLCCR
    

Molecular Weight10460.78 Da

Isoelectric Point (pI)8.30

Net Charge (pH 7.0)1.46

Net Charge (pH 7.4) 1.14

Charge Density (pH 7.0) 0.0156

GRAVY Index-0.26

Hydrophobic Moment 0.89

Boman Index-0.14

Instability Index48.49

Aliphatic Index 85.32

Aromaticity 0.0532

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4644.23

LogP -57.05

H-bond Donors 174.0

H-bond Acceptors 150.0

Rotatable Bonds 358.0

Heavy Atoms 728.0

Ring Count 6.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0064471 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic