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MYP_154164
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Basic Information
Protegrin 1 (5-16), PG-1 (5-16)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
12 amino acids
C64H105N21O14S4
Standard
Sequence
LCYCRRRFCVCV
Physicochemical Analysis
1520.91 Da
8.98
2.72
2.46
0.2266
0.85
0.25
-0.15
92.07
80.83
0.1667
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
589.35
-4.21
27.0
21.0
47.0
103.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0357240 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
4
Bio-Activity Profile
Antimicrobial Antibacterial
methicillin-resistant Staphylococcus aureus
1 μg/mL
MIC
PMID10931444 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10931444/
RECORD: Rec_0365985 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
N. gonorrhoeae F-62
2.3 μg/mL
MIC
PMID15629531 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15629531/
RECORD: Rec_0372601 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
4
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
2 μg/mL
MIC
PMID10931444 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10931444/
RECORD: Rec_0386149 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus 930918-3
0.40
MIC
PMID9009324;9596706 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9009324/
RECORD: Rec_0396794 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
8.8 μg/mL
MIC
PMID15629531 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15629531/
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