Peptide Database

Peptide NameCcl (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length175 amino acids

Chemical FormulaC735H1131N223O243S4

DescriptionStandard

        MYIQYVDFNLLVLNVKEENDMSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSGPGWGTTHTPNGDIHNYNPGEFGHGGNKPGGNGGNSGNHRGSSGGRQSSATAMAFGLPALATPGSGGLALAVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSDCKR
    

Molecular Weight17107.45 Da

Isoelectric Point (pI)6.49

Net Charge (pH 7.0)-1.07

Net Charge (pH 7.4) -1.57

Charge Density (pH 7.0) -0.0061

GRAVY Index-0.39

Hydrophobic Moment 0.42

Boman Index0.12

Instability Index27.48

Aliphatic Index 59.71

Aromaticity 0.0629

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7340.86

LogP -107.67

H-bond Donors 247.0

H-bond Acceptors 251.0

Rotatable Bonds 549.0

Heavy Atoms 1205.0

Ring Count 29.0

Amide Bonds 192.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161185 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyColicin/Bacteriocin

Tax ID573

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence