Peptide Database

Peptide NameHepcidin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC368H582N104O123S10

DescriptionStandard

        MKTFSAAVTVAVVLVFICIQQSSATSPEVQELEEAVSSDNAAAEHQEQSADSWMMPQNRQKRDVKCGFCCKDGGCGVCCNF
    

Molecular Weight8751.83 Da

Isoelectric Point (pI)4.68

Net Charge (pH 7.0)-4.46

Net Charge (pH 7.4) -4.85

Charge Density (pH 7.0) -0.0551

GRAVY Index-0.09

Hydrophobic Moment 0.52

Boman Index0.03

Instability Index63.55

Aliphatic Index 62.59

Aromaticity 0.0617

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3672.52

LogP -45.89

H-bond Donors 130.0

H-bond Acceptors 130.0

Rotatable Bonds 292.0

Heavy Atoms 605.0

Ring Count 9.0

Amide Bonds 90.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0122374 VERIFIED: NO

Provenance & Taxonomy

OrganismParalichthys olivaceus [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0264693 VERIFIED: NO