Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC359H579N95O88S9

DescriptionStandard

        MKFLLLTLAVLLLMSQLIPGDTQRCWNLLGKCRHRCSKKDSVYVYCTNGKMCCVKPKYQPKPKPSWLF
    

Molecular Weight7922.61 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)9.52

Net Charge (pH 7.4) 9.15

Charge Density (pH 7.0) 0.1400

GRAVY Index-0.08

Hydrophobic Moment 0.55

Boman Index0.00

Instability Index29.44

Aliphatic Index 87.35

Aromaticity 0.1029

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2941.56

LogP -20.36

H-bond Donors 108.0

H-bond Acceptors 108.0

Rotatable Bonds 261.0

Heavy Atoms 551.0

Ring Count 15.0

Amide Bonds 72.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0173720 VERIFIED: NO

Provenance & Taxonomy

OrganismFukomys damarensis [Animal]

FamilyBeta-defensin; Defensin

Tax ID885580

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic