Peptide Database

Peptide NameAllatostatin-3

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Invertebrate inhibitory neuropeptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Invertebrate inhibitory neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC86H131N19O24S

DescriptionStandard

        QVSLKYPEGKMYSFGL
    

Molecular Weight1847.14 Da

Isoelectric Point (pI)8.43

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0474

GRAVY Index-0.31

Hydrophobic Moment 0.24

Boman Index0.10

Instability Index47.80

Aliphatic Index 66.88

Aromaticity 0.1875

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 704.38

LogP -4.55

H-bond Donors 24.0

H-bond Acceptors 26.0

Rotatable Bonds 60.0

Heavy Atoms 130.0

Ring Count 4.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0060254 VERIFIED: YES

Provenance & Taxonomy

OrganismRhodnius prolixus [Animal]

FamilyAllatostatin

Tax ID13249

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Invertebrate inhibitory neuropeptide

RECORD: Rec_0183126 VERIFIED: YES

Provenance & Taxonomy

OrganismRhodnius prolixus [Animal]

FamilyAllatostatin

Tax ID13249

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0386735 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/