Peptide Database

Peptide NameTransforming growth factor beta-1

Function Ontology

Antimicrobial ▸ Antifungal

Immunology ▸ Immune modulation ▸ Cytokine modulation

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC576H876N152O159S10

DescriptionStandard

        ALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
    

Molecular Weight12794.69 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)3.97

Net Charge (pH 7.4) 3.46

Charge Density (pH 7.0) 0.0354

GRAVY Index-0.25

Hydrophobic Moment 0.63

Boman Index0.03

Instability Index25.22

Aliphatic Index 76.61

Aromaticity 0.1250

Extinction Coeff. Reduced 28420.00

Extinction Coeff. Oxidized 28920.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4960.24

LogP -43.04

H-bond Donors 177.0

H-bond Acceptors 176.0

Rotatable Bonds 403.0

Heavy Atoms 897.0

Ring Count 29.0

Amide Bonds 122.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267902 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTGF-beta family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-16; 15-78; 44-109; 48-111

Bio-Activity Profile

Function

Cytokine Growth factor TGF-beta family Antifungal Growth factor signaling Host defense