Peptide Database

Peptide NameSLAY-screened peptide P5702

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC108H156N24O24S2

DescriptionStandard

        ACPTLPWCPWITHAVGLYPI
    

Molecular Weight2238.67 Da

Isoelectric Point (pI)6.76

Net Charge (pH 7.0)-0.14

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0069

GRAVY Index0.74

Hydrophobic Moment 0.27

Boman Index0.51

Instability Index59.41

Aliphatic Index 102.50

Aromaticity 0.1500

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 702.01

LogP -0.87

H-bond Donors 25.0

H-bond Acceptors 27.0

Rotatable Bonds 56.0

Heavy Atoms 158.0

Ring Count 10.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0058988 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/