Peptide Database

Peptide NameZilucoplan

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ Complement inhibitor

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard Statusnot Standard

Sequence Length18 amino acids

Chemical Formula-

Descriptioncontains X representing unresolved or non-standard residue

        KVERFDXXYXEYPXKXGX
    

Molecular Weight0.00 Da

Isoelectric Point (pI)0.00

Net Charge (pH 7.0)0.00

GRAVY Index0.00

Boman Index0.00

Instability Index0.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0145341 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyComplement inhibitor

Tax ID32630

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermAcetylation

Other ModsNon-standard residues/X at 7, 8, 10, 14, 16, 18; Lipidation

Bio-Activity Profile

Function

Complement inhibitor Immunomodulatory

TargetComplement component C5

Half-LifeClinical/Human: 172 h