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MYP_154048
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Basic Information
Gomesin [PYA1TOAC]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
18 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XCRRLCYKQRCVTYCRGR
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0032806 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Latarcin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Aspergillus fumigatus
1.6-3.15 μM
MIC
PMID16235231;23426877;17027634 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16235231/
RECORD: Rec_0034844 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Latarcin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 1
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bacillus megaterium
1.28 μM
MIC
PMID16235231;23426877;17027634 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16235231/
RECORD: Rec_0035017 VERIFIED: YES
Provenance & Taxonomy
Acanthoscurria gomesiana [Animal]
Latarcin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
non-canonical residue code at 1
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
4 μM
MIC
PMID10942757;28741926 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10942757/
RECORD: Rec_0036059 VERIFIED: YES
Provenance & Taxonomy
Acanthoscurria gomesiana [Animal]
Latarcin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
non-canonical residue code at 1
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 43300 methicillin-resistant Staphylococcus aureus
128 μg/mL
PMID27331141 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27331141/
RECORD: Rec_0036565 VERIFIED: YES
Provenance & Taxonomy
Acanthoscurria gomesiana [Animal]
Latarcin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
non-canonical residue code at 1
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Nocardia asteroides
1.6-3.15 μM
MIC
PMID10942757;28741926 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10942757/
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