‹ ›
MYP_154043
← PREVIOUS NEXT → BACK
Basic Information
Macaque histatin (His-rich; M-Histatin 1; primates, mammals, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
38 amino acids
C207H294N78O58
Standard
Sequence
DSHEERHHGRHGHHKYGRKFHEKHHSHRGYRSNYLYDN
Physicochemical Analysis
4803.04 Da
9.60
3.64
2.91
0.0957
-2.46
0.56
-0.58
40.94
10.26
0.1316
5960.00
5960.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2228.67
-25.42
81.0
71.0
159.0
343.0
15.0
39.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0175187 VERIFIED: YES
Provenance & Taxonomy
Macaca fascicularis [Animal]
Histatin
9541
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperPubMed PMID: 2229609 PMID2229609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2229609/
RECORD: Rec_0197512 VERIFIED: YES
Provenance & Taxonomy
Crab eating [Animal]; Mammalia [Animal]
Histatin
33208; 40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID2229609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2229609/
RECORD: Rec_0265418 VERIFIED: YES
Provenance & Taxonomy
Macaca fascicularis [Animal]
Histatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0283893 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0287697 VERIFIED: YES
Provenance & Taxonomy
Crab eating macaque [Animal]
Histatin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Rich in H. Chemical modification: a phosphoserine at residue 2
Bio-Activity Profile
Antifungal
Candida albicans. Updated 7/2021
PaperPrimary structure and anticandidal activity of the major histatin from parotid secretion of the subhuman primate, Macaca fascicularis.
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2