Peptide Database

Peptide NameMERS-5HB

Function Ontology

Antiviral

Standard StatusStandard

Sequence Length355 amino acids

Chemical FormulaC1626H2629N451O547S5

DescriptionStandard

        GITQQVLSENQKLIANKFNQALGAMQTGFTTTNEAFQKVQDAVNNNAQALSKLSAELSNTFGAISASIGDIIQRLDVLESGGRGGSIPNFGSLTQINTTLLDLTYEMLSLQQVVKALNESYIDLKELGNYGGSGGSGGGITQQVLSENQKLIANKFNQALGAMQTGFTTTNEAFQKVQDAVNNNAQALSKLSAELSNTFGAISASIGDIIQRLDVLESGGRGGSIPNFGSLTQINTTLLDLTYEMLSLQQVVKALNESYIDLKELGNYGGSGGSGGGITQQVLSENQKLIANKFNQALGAMQTGFTTTNEAFQKVQDAVNNNAQALSKLSAELSNTFGAISASIGDIIQRLDVLE
    

Molecular Weight37408.28 Da

Isoelectric Point (pI)4.66

Net Charge (pH 7.0)-10.19

Net Charge (pH 7.4) -10.47

Charge Density (pH 7.0) -0.0287

GRAVY Index-0.14

Hydrophobic Moment 0.61

Boman Index0.09

Instability Index12.13

Aliphatic Index 94.59

Aromaticity 0.0563

Extinction Coeff. Reduced 8940.00

Extinction Coeff. Oxidized 8940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0419224 VERIFIED: YES

Provenance & Taxonomy

OrganismMiddle East respiratory syndrome-related coronavirus [Virus]

FamilyHR1-derived fusion inhibitor

Tax ID1335626

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

TargetMiddle East respiratory syndrome-related coronavirus

Activity1 μg/mL

MethodIC50