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MYP_154002
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
18 amino acids
C80H150N36O19S6
Standard
Sequence
GVCRCLCRRGVCRCICRR
Physicochemical Analysis
2112.67 Da
9.69
5.70
5.41
0.3167
0.22
0.63
-0.44
79.07
75.56
0.0000
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
929.42
-11.53
43.0
31.0
71.0
141.0
0.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0162284 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 33.3%, T 33.3%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0232360 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544;0
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Backbone-cyclized theta-defensin scaffold
Bio-Activity Profile
Antiviral Entry inhibitor
Herpes simplex virus 1 (Virus entry); ME-180
MTT assay
PaperTheta defensins protect cells from infection by herpes simplex virus by inhibiting viral adhesion and entry. | Yasin B, Wang W, Pang M, Cheshenko N, Hong T, Waring AJ, Herold BC, Wagar EA, Lehrer RI. | J Virol. 2004 | PMID:15113897 PMID15113897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15113897/
RECORD: Rec_0316828 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
Bacillus anthracis Sterne 7702
PMID16790431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16790431/
RECORD: Rec_0352860 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544;0
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Backbone-cyclized theta-defensin scaffold
Bio-Activity Profile
Antiviral Entry inhibitor
Herpes simplex virus 2 (Virus entry); ME-180
MTT assay
PaperTheta defensins protect cells from infection by herpes simplex virus by inhibiting viral adhesion and entry. | Yasin B, Wang W, Pang M, Cheshenko N, Hong T, Waring AJ, Herold BC, Wagar EA, Lehrer RI. | J Virol. 2004 | PMID:15113897 PMID15113897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15113897/