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MYP_153996
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Basic Information
MIA-602
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C149H245N43O43S
Standard
Sequence
YADAIFTNSYRKVLGQLSARKLLQDIMSR
Physicochemical Analysis
3358.87 Da
9.99
2.76
2.55
0.0951
-0.22
0.61
-0.09
37.70
101.03
0.1034
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1441.11
-13.75
52.0
47.0
115.0
236.0
3.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0135195 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GHRH/CRF
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
PEGylation
Bio-Activity Profile
Endocrine
0.00106 μM
EC50
Human plasma, in vitro; 12960 s
PMID14499707 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499707/
RECORD: Rec_0145899 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GHRH/CRF
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
PEGylation on Lys12
Bio-Activity Profile
Endocrine
Reporter gene assay
Human plasma, in vitro; 36000 s
PMID14499707 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499707/
RECORD: Rec_0150223 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GHRH/CRF
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
PEGylation on Lys21
Bio-Activity Profile
Endocrine
Reporter gene assay
Human plasma, in vitro; 14400 s
PMID14499707 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499707/
RECORD: Rec_0158627 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
GHRH/CRF
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Chlorpheniramine M
Amidation
Bio-Activity Profile
Endocrine
HPLC
Porcine plasma, in vitro; 3600 s
PMID1826667 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1826667/
RECORD: Rec_0181287 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GHRH/CRF
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Endocrine
GH releasing activity = 100%
Radioimmunoassay
Rat plasma (i/v and s/c route of injection), in vivo; 372 s
PMID2896343 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2896343/
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